Animal and Human Studies on Ferrous Fumarate, an Oral Hematinic
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منابع مشابه
Animal and human studies on ferrous fumarate, an oral hematinic.
By M. C. BERENBAUM, K. J. CHILD, B. DAVIS, HELEN M. SHARPE AND E. G. ToMIci T HE ORAL TREATMENT of hypochromic anemia with inorganic salts of iron occasionally results in gastrointestinal distress, and massive doses produce necrosis of the gastric mucosa and liver ( Forbes, 1947; Smith, 1952; Swift, Cefalu and Rubell, 1952; Luongo and Bjornson, 1954) . A recent survey ( Hoppe, Marcelli and Tain...
متن کاملLow-dose oral ferrous fumarate aggravated intestinal inflammation in rats with DSS-induced colitis.
BACKGROUND Oral ferrous iron therapy may reinforce intestinal inflammation. One possible mechanism is by catalyzing the production of reactive oxygen species. We studied the effects of low-dose oral ferrous fumarate on intestinal inflammation and plasma redox status in dextran sulfate sodium (DSS)-induced colitis in rats. METHODS Forty male Wistar rats were divided into 5 groups: no intervent...
متن کاملOral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease.
OBJECTIVE Iron therapy may reinforce intestinal inflammation by catalysing production of reactive oxygen species. The effects of oral ferrous fumarate and intravenous iron sucrose on clinical disease activity and plasma redox status were investigated in patients with inflammatory bowel disease (IBD). MATERIAL AND METHODS Nineteen patients with iron deficiency anaemia and Crohn's disease (11) ...
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متن کاملFerrous fumarate fortification of a chocolate drink powder.
An evaluation was made into the usefulness of ferrous fumarate as an iron fortificant for an experimental chocolate drink powder targetted to children and adolescents. Organoleptically ferrous furmarate was acceptable when the chocolate drink powder was reconstituted in milk or water that was heated to less than 80 degrees. Unacceptable colour changes occurred, however, when boiling milk or wat...
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ژورنال
عنوان ژورنال: Blood
سال: 1960
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v15.4.540.540